Cooperation of BH3-only proteins in killing neurons
Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins | PNAS
Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells | Science Advances
Frontiers | Targeting the Bcl-2 Family in B Cell Lymphoma
The BCL-2 protein family, BH3-mimetics and cancer therapy | Cell Death & Differentiation
Basal Patologi KU - BAD, BID and PUMA proteins shift the balance between the pro-apoptotic and anti-apoptotic family members by neutralizing the actions of anti-apoptotic proteins like BCL2 and BCL-XL, thereby promoting
PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis | Nature Chemical Biology
Biomolecules | Free Full-Text | The Bcl-2 Family: Ancient Origins, Conserved Structures, and Divergent Mechanisms
A model for PUMA-mediated apoptosis. PUMA activates Bax/Bak indirectly... | Download Scientific Diagram
BCL-2 family: integrating stress responses at the ER to control cell demise | Cell Death & Differentiation
Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment - ScienceDirect
Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells | Science Advances
A novel Bcl-2 inhibitor, BM-1197, induces apoptosis in malignant lymphoma cells through the endogenous apoptotic pathway | BMC Cancer | Full Text
Why do BCL-2 inhibitors work and where should we use them in the clinic? | Cell Death & Differentiation
IJMS | Free Full-Text | Co-Operativity between MYC and BCL-2 Pro-Survival Proteins in Cancer
BCL-2
Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance | Cell Death & Disease
Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance - ScienceDirect
BCL‐2‐family protein tBID can act as a BAX‐like effector of apoptosis | The EMBO Journal
PUMA decreases the growth of prostate cancer PC-3 cells independent of p53
